Promising Technologies

Pharmaceutical Composition for preventing or treating sensorineural hearing loss and chronic otitis media

  • Inventor
    Prof. Jinsei Jung
    MD, Ph.D.
    Dept. of Otorhinolaryngology
  • Category
    Infectious disease, Hearing Loss
  • Keywords
    Hearing loss, Chronic Otitis Media, Antibiotics, Resistance
  • Current development stage
    General list: TRL 4 Technology validated in lab
  • Patent Status
    KR/10-2019-0097557
    PCT/KR2019/010998
  • Brief Description
    By eliminating pathogens and fine-tuning the immune response, the treatment and prevention of sensorineural hearing loss induced by pathogens can be expected. However, the mechanisms associated with this fine immunological modulation have not been disclosed until now. This technique confirms that threshold values ​​for hearing response contribute to hearing recovery compared with control mice when peptide L is externally treated with Pseudomonas infected mice, which is related with anti-bacterial function of L peptide. Peptide L is a potential drug candidate for the treatment of sensorineural hearing loss as well as chronic otitis media.
  • Representative figure

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