Promising Technologies

The devices for predicting axillary lymph node metastasis in breast cancer

  • Inventor
    Joon Jeong
    MD., PhD
    Dept. of Surgery
  • Category
    Breast Cancer, Medical Device
  • Keywords
    Ultrasound elastography, Axillary lymph node metastasis, Breast cancer
  • Current development stage
  • Patent Status
    KR patent application
    PCT patent application
    PCT/KR2019/013174
  • Brief Description
    This device, based on ultrasound elastography, predicts the axillary lymph node metastasis in patients with breast cancer during the surgery. This methodology involves the use of biological samples, including sentinel lymph nodes and fat tissue surrounding lymph glands. The first step is to measure the size and elasticity values such as mean stiffness and elasticity ratio of the excised sentinel lymph node by using B-mode ultrasound and shear wave elastography. Then, the possibility of lymph node metastasis is automatically calculated after entering the node size and elasticity values.

    Sentinel lymph node biopsy has become a standard method for axillary staging in clinically node-negative patients with breast cancer. In addition, intraoperative pathologic assessment of sentinel lymph nodes enables one stage operation by determining the axillary lymph node dissection. However, it requires skilled pathologists and equipment, which increases the operation time and the costs. To overcome these disadvantages, we have developed a device based on ultrasound elastography that can predict axillary lymph node metastasis easily and quickly during breast surgery.
  • Representative figure

LIST